Understanding Chronic Ischemic Heart Disease Today

Presented By:		Robert L. Wilensky, MD, FACC, FAHA Professor of Medicine University of Pennsylvania School of Medicine Director, Interventional Cardiology Research University of Pennsylvania Health System Philadelphia, Pennsylvania

Program Description:	This CME activity consists of an educational component (ie, slides, audio lecture, newsletter) in an electronic format, followed by an online post-test. Estimated time to complete this activity, including review of materials, is 45 minutes.
General Information:	Requirements for Successful Completion: This CME activity consists of an educational component (ie, slides, audio lecture, newsletter) in an electronic format, which is followed by an online post-test. There is no fee to participate in this CME activity or to receive CME credit. Certificates are awarded upon successful completion (80% proficiency) of the post-test. In order to receive credit, participants must view the presentaion in its entirety. Media: Internet Release Date:    January 28, 2008 Expiration Date:  January 28, 2010
Target Audience:	Cardiologists, Interventional Cardiology, Internal Medicine Specialist
Program Overview:	Evolving concepts of the fundamental basis of chronic IHD include a growing appreciation of the remarkable heterogeneity of anatomic disease in all patients. Lesions within a single coronary artery may vary significantly in the extent and severity of plaque formation, luminal obstruction, inflammation, and likelihood of rupture. The clinical manifestations of IHD are due both to obstructive stable lesions and to nonobstructive vulnerable plaques. Inevitably, both types of lesions are present concurrently in the same patient and need to be addressed by clinicians using selective management strategies. Due to the diffuse nature of coronary atherosclerosis and its complex pathophysiology, patients often continue to experience angina despite coronary revascularization and treatment with traditional antianginal treatments. This CME activity is designed to increase physician understanding of the heterogeneity of chronic IHD, including the pathophysiology and clinical manifestations of obstructive stable lesions and nonobstructive vulnerable plaques. Moreover, it will provide an update on new treatment strategies.
Learning Objectives:	Describe the pathophysiologic differences between obstructive stable lesions and nonobstructive vulnerable plaque, and apply this knowledge to a comprehensive approach to patients with atherosclerotic vascular disease Appreciate that angina continues to impose a socioeconomic burden on patients despite coronary revascularization and treatment with traditional antianginal medication, and to integrate pharmacologic therapy and mechanical intervention in a rational, evidence-based manner Compare and contrast the different mechanisms of myocardial ischemia, and apply this knowledge to evaluation and management of patients with chronic stable angina
Faculty Disclosure:	The University of Florida College of Medicine has a conflict of interest policy that requires course faculty to disclose any real or apparent commercial financial affiliations related to the content of their presentations/materials. It is not assumed that these financial interests or affiliations will have an adverse impact on faculty presentations; they simply are noted here to fully inform participants. Robert L. Wilensky, MD, has indicated that he has a financial arrangement or affiliation with GlaxoSmith Kline, Boston Scientific Corp, AstraZeneca, TopSpin Medical and Johnson & Johnson. The types of affiliation/financial interest are grant/research support, consultant agreements and stock shareholder.
Continuing Medical Education Credit:
	Accreditation
	The University of Florida College of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
	Credit
	The University of Florida College of Medicine designates this educational activity for a maximum of .75 AMA PRA Category 1 CreditsTM. Physicians should only claim credit commensurate with the extent of their participation in the activity.
	This continuing education activity was planned in accordance with the ACCME essentials and reviewed by Carl J. Pepine, MD, Program Chair.
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Commercial Support:	This CME activity is supported by an educational grant from CV Therapeutics.
System Requirements:	In order to view the presentation, your computer must have a media player such as Windows Media Player, Quicktime, or RealOne.
CME Contact:	For any question regarding this Internet CME activity, please contact the Office of Continuing Medical Education at 352-265-8081.
	The University of Florida College of Medicine has received permission to use this copyrighted material within a CME activity on the internet.

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